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Two people were killed and more than 50 injured in a 40-car pileup on Interstate 10 in New Orleans on Thursday. Twenty-two people were transferred to hospitals with critical to minor injuries, while another 37 people reportedly refused treatment, New Orleans police said. The accident started around 4:30 a.m. in the westbound land of the interstate, and the cause of the pileup remains uncertain. Both the eastbound and westbound lanes of the interstate were closed, and police did not say when it would be reopened.