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Syria’s national security building was attacked by a suicide bomber on Wednesday, killing both the defense minister and President Bashar al-Assad's brother-in-law, and critically injuring other ministers and security officials who were inside for a meeting at the time. The Damascus attack came as Syrian officials claimed to be fighting off a major offensive by rebel forces, and was the first since the uprising started 17 months ago in which high-ranking members of Assad's elite. The White House said that Assad's regime is "losing control."